Biological materials required:
- Tissue samples (excised formations, biopsies).
- Fluid samples - Intra-vitam diagnosis Feline Infectious Peritonitis.
Cell Markers |
Identification |
CD3 |
T- lymphocyte |
CD79a |
B lymphocyte/Plasma cell |
CD18 (canin) |
Macrophage/Histiocyte |
CD11D (canin) |
Macrophage (in spleen and bone marrow) |
Desmin/Alpha-actine |
Leiomyocyt/Rhabdomyocyt |
Vimentin |
Mesenchymal cells |
Pan-Cytokeratin |
Epithelial cells |
CD117 (c-Kit) |
Mast cells Interstitial cells – cabaline (Cajal cells) |
Factor VIII |
Endothelial cells |
CD45 R |
B lymphocyte (feline) |
S-100 |
Schwann cells/Melanocyte |
Synaptophysin |
Neuroendocrine cells/ganglionar cells |
Neurofilaments |
Neurons |
Caspase 3 |
Apoptotic cells |
Histiocytic antigen (mieloid) |
Neutrophils, monocyte and young macrophages |
PCNA |
Cell growth factors |
GFAP |
Astrocite |
Lysozyme |
Macrophages |
Pax-5 |
B lymphocytes |
MHC II Ag |
Major histocompatibility complex type II |
Mast Cell Triptaze |
Mast cell tryptase |
Melan A |
Melanocite |
Albumin |
Albumin |
TNF-alpha (canine) |
Tumoral necrosis factor |
IL-6 (canine) |
Interleukin 6 |
Infectious agent |
Diagnosis |
Feline coronavirus (FCoV) |
Feline Infectious Peritonitis (FIP) |
Feline Calicivirus (FCV) |
Feline calicivirosis |
Feline Herpesvirus (FHV) |
Feline Herpesvirosis |
Feline leukemia virus (FeLV) |
Feline viral leukemia |
Feline/Canine Parvovirus (FPV/CPV) |
Feline/Canine Parvovirosis |
Canine adenovirus |
Infectious Canine Hepatititis (Rubarth disease) |
Canine Distemper Virus (CDV) |
Carre disease/ Canine Distemper Diseases |
Toxoplasma gondii |
Toxoplasmosis |
Neospora caninum |
Neosporosis |
Helicobacter spp. |
Helicobacter infection |
Prognostic factors |
Prognostic factors – oral melanoma/dermal canine (Ki-67 + COX-2 score) |
Prognostic factors – canine mammary carcinoma/feline (COX-2 score) |
Prognostic factors – canine osteosarcoma (COX-2 score) |
Prognostic factors – Mast cell tumor (C-kit pattern + Ki-67 score) |